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目的:观察米力农治疗顽固性心力衰竭的疗效和安全性。方法:50例顽固性心力衰竭心功能Ⅲ~Ⅳ级患者随机分为治疗组和对照组,治疗组再加用米力农,予以50μg/kg静脉注射10 min,再以0.5μg/(kg.min)静脉滴入,7 d为1个疗程,对照组除米力农外其他治疗相同。结果:治疗1周后治疗组总有效率为88%,对照组总有效率为56%(P<0.05)。结论:米力农静脉滴入治疗能有效改善顽固性心力衰竭的心功能。
Objective: To observe the efficacy and safety of Milrinone in the treatment of refractory heart failure. Methods: Fifty patients with refractory heart failure of grade Ⅲ ~ Ⅳ were randomly divided into treatment group and control group. The treatment group was given Milrinone intravenously at 50μg / kg for 10 minutes and then treated with 0.5μg / (kg). min) intravenous infusion, 7 d for a course of treatment, the control group except milrinone other treatment the same. Results: After 1 week of treatment, the total effective rate was 88% in the treatment group and 56% in the control group (P <0.05). Conclusion: Milrinone intravenous infusion therapy can effectively improve the heart function of refractory heart failure.