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人免疫缺陷病毒Ⅰ型(HIV-1)是引起获得性免疫缺陷综合征(AIDS)的一类主要的病毒, 它主要感染4CD+的T淋巴细胞, 从而造成机体免疫系统的损伤[1]. HIV-1生命周期的起点是病毒进入宿主细胞, 这个过程首先依赖于病毒表面囊膜糖蛋白gp120与细胞表面受体CD4分子以及辅助受体CXCR4或CC
Human immunodeficiency virus type 1 (HIV-1) is a major class of virus that causes Acquired Immunodeficiency Syndrome (AIDS), which infects mainly CD4 + T lymphocytes, resulting in damage to the body’s immune system.1 HIV The beginning of the -1 life cycle is the entry of the virus into the host cell, a process that relies primarily on the viral surface glycoprotein gp120 and the cell surface receptor CD4 molecule as well as the co-receptor CXCR4 or CC