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本文目的在于用每日标准剂量的异烟肼(H)、利福平(R)及链霉素(S)外加吡嗪酰胺(Z)治疗肺结核,经4个月治疗后,能否消灭复发,如不能,则6个月治疗能否消灭复发。两组病人,首先用 SHRZ 治疗2个月,以后一组给 HRZ,另一组给 HR。每组总疗程又分为6个月和4个月两组。本文报告30个月的结果,即6个月治疗后的24个月及4个月治疗后26个月的细菌学复发率。对象为15岁及以上的患肺结核病的华人、马来西亚人及印度人,痰耐酸菌涂片阳性、未受过抗痨化疗者。共400例,供分析者363例。随机分为2组,每组又随机分为2个不同治疗期组。日剂量:S0.75g 肌注;H300mg,R450或600mg,Z1.5或2g 口服。病人体重超过50kg 者,R 及 Z 给予较大的剂量。口服药每天在同一时间内监督下1次服完。病人胸部检查,第18
This article aims to treat tuberculosis with daily standard doses of isoniazid (H), rifampin (R), and streptomycin (S) plus pyrazinamide (Z), and to eradicate relapse after 4 months of treatment If not, then 6 months treatment can eliminate recurrence. Two groups of patients, first with SHRZ treatment for 2 months, after a group to HRZ, the other group to HR. The total course of treatment is divided into two groups of 6 months and 4 months. This article reports the 30-month outcome of the bacteriological relapse rate at 24 months after 6 months and 26 months after treatment at 4 months. The target is Chinese, Malaysian and Indian who are suffering from pulmonary tuberculosis 15 years and older. The sputum acid-fast bacilli smear is positive and has not been treated with anti-tuberculosis chemotherapy. A total of 400 cases for 363 cases of analysts. Randomly divided into two groups, each group was randomly divided into two different treatment groups. Daily dose: S0.75g intramuscular; H300mg, R450 or 600mg, Z1.5 or 2g orally. Patients weighing more than 50kg, R and Z given a larger dose. Oral medication under supervision at the same time 1 serving day. Patient Chest Examination, No. 18