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自1947年皮质激素用于治疗类风湿性关节炎取得良好疗效以后,皮质激素开始受到广泛注意,临床应用日趋普遍。至六十年代末,皮质激素几乎成了“医治百病的妙药”。随着使用经验的增多,在风靡一时之后,又趋于冷落。对任何一种药物来说,做出公正的评价还是必要的。就外科领域而言,皮质激素仍有其不可忽视的价值,但绝不宜滥用,而且常常只能起到辅助治疗的作用。皮质激素属于甾醇类,包括肾上腺皮质所分泌的多种激素,根据其生理功能可分为三类。①糖皮质激素:主要是皮质醇(Cortisol)和皮质酮(Corticosterone)。②盐皮质激素:主要是醛固酮。③氮皮质激素:即性皮质激素,以雄激素为主,也有少量雌激素。临床通常使用的皮质激素是指糖皮质激素(Glu
Since 1947, corticosteroids for the treatment of rheumatoid arthritis and achieved good results, corticosteroids began to receive widespread attention, the increasingly widespread clinical application. By the late 1960s, corticosteroids almost became the “cure” for everything. With the increasing use of experience, after the rage, they tend to fall out. For any kind of medicine, make a fair evaluation is still necessary. In the field of surgery, corticosteroids still have their value can not be ignored, but must not be abused, and often can only play a role in adjuvant therapy. Corticosteroids are sterols, including a variety of hormones secreted by the adrenal cortex, according to their physiological functions can be divided into three categories. ① glucocorticoid: mainly cortisol (Cortisol) and corticosterone (Corticosterone). Mineralocorticoid: mainly aldosterone. Â ’¢ aortic corticotropin: that is, corticosteroids, androgen-based, but also a small amount of estrogen. Corticoids commonly used clinically are glucocorticoid (Glu