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目的 研究激光治疗前列腺增生症患者血清总前列腺特异性抗原 (PSA) ,游离 PSA和游离 /总 PSA比值的变化 ,确定游离 /总 PSA比值的可靠性 .方法 应用 830 e半导体激光仪对 10 0例前列腺增生症患者行组织内激光凝固治疗 ,用酶联免疫法于术前 1h和术后 2 4h检测患者血清总 PSA和游离 PSA值 ,并计算游离 /总 PSA比值 .结果 术后总 PSA和游离 PSA值与术前比均明显升高 (P<0 .0 0 1和 P<0 .0 5 ) ,游离 /总 PSA比值术前术后无显著差异 (P=0 .10 3) .结论 游离 /总 PSA比值可作为激光治疗前列腺增生症可靠指标
Objective To study the changes of total PSA, free PSA and free PSA / total PSA in patients with benign prostatic hyperplasia treated by laser and to determine the reliability of free PSA / total PSA.METHODS A total of 100 patients with benign prostatic hyperplasia Patients with benign prostatic hyperplasia were treated with laser photocoagulation and serum total PSA and free PSA values were measured by enzyme-linked immunosorbent assay (ELISA) at 1 hour before operation and 24 hours after operation.Results The total PSA and free PSA The PSA value was significantly higher than that before operation (P0.01 and P0.05), but there was no significant difference between the free PSA and preoperative PSA (P = 0.103) / Total PSA ratio can be used as a reliable indicator of laser treatment of benign prostatic hyperplasia