本工作在大鼠烫伤后的不同时间,分别从侧脑室注射Dyn A_(1-13)抗血清,观察动物存活时问、血压和心率的变化,以探讨中枢给予Dyn A_(1-13)抗血清对烫伤休克的影响。实验结果表明,中枢给予Dyn A_(1-13)抗血清,与外周静脉给予一样可改善大鼠心血管功能、延长动物的存活时间。这提示中枢神经系统的强啡肽也参与 In this study, Dyn A_ (1-13) antiserum was injected into the lateral ventricle at different time points after scald in rats, and the changes of survival, blood pressure and heart rate were observed to investigate the effects of Dyn A_ (1-13) Effect of Serum on Scald Shock. Experimental results show that the central administration of Dyn A_ (1-13) antiserum, as well as peripheral venous administration can improve cardiovascular function and extend the survival time of animals. This suggests that the dynorphin of the central nervous system is also involved