论文部分内容阅读
合理应用抗菌药,能明显降低非污染手术的术后感染率。但必须选择合适的药物,并采用正确的给药方案,才能达到目的。①药物的选择:根据预防性应用抗菌药的选药原则,头孢唑啉等第一代头孢菌素,对心血管、肺、妇产科、胆道、胃和十二指肠、耳、咽及骨关节手术后感染的最主要致病菌,具有良好的抗菌活性,因而宜作首选药。其中,心血管和关节手术后感染的主要病原菌为葡萄球菌,故也可选用苯唑青霉素、邻氯青霉素。某些医院将氯基糖甙类抗生素或第三代头孢菌素作为预防手术感染用药,前者耳、肾毒性明显,且抗菌谱过广,易引起其他耐药菌感染;后者价格昂贵,抗菌谱
Appropriate use of antimicrobial agents, can significantly reduce the postoperative infection rate of non-polluting surgery. But you have to choose the right medicine and use the right dosage regimen to get there. ① choice of drugs: According to the principle of prophylactic antibacterial drug selection, cefazolin and other first-generation cephalosporins, cardiovascular, lung, obstetrics and gynecology, biliary, stomach and duodenum, ear, pharynx and Bone and joint surgery after infection the most important pathogens, has good antibacterial activity, and therefore should be the preferred drug. Among them, the main pathogen of cardiovascular and joint surgery after infection is Staphylococcus aureus, it can also be used oxacillin, chlorpheniramine. In some hospitals, chloro-glycoside antibiotics or third-generation cephalosporins are used as prophylactic surgical infections. The former has obvious auricle and nephrotoxicity and the antibacterial spectrum is too broad, which can easily lead to infection with other drug-resistant bacteria. The latter is expensive and antibacterial Spectrum