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作者报道了从各型胃病患者胃粘膜中分离的112株幽门螺杆菌,用聚丙烯酰胺凝胶电泳(SDS-PAGE)及Westernblots分析,可将HP菌分为Ⅰ-Ⅳ型,而其中Ⅳ型又分为Ⅳ-1至Ⅳ-5五个亚型;不同HP间存在明显的蛋白抗原差异和LPS/LOS的表达差异;为今后开展HP疫苗研究提供了重要线索。
The authors report 112 Helicobacter pylori isolates from the gastric mucosa of various types of gastric patients, which were classified into type I-IV by polyacrylamide gel electrophoresis (SDS-PAGE) and Western blot analysis, of which Type IV There are five subtypes Ⅳ-1 to Ⅳ-5. There are obvious differences of protein antigen and LPS / LOS between different HP, which provide important clues for HP vaccine research in the future.