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对近年来温胆片治疗相关疾病的临床疗效及药理研究进行综述。温胆片由温胆汤化裁而来,具有理气化痰、清胆和胃、清心解郁等作用,目前已被临床广泛用于治疗神经系统疾病、代谢性疾病和心血管系统疾病,疗效确切。近些年有关温胆片的文献资料表明:温胆片在治疗广泛性焦虑障碍、动脉粥样硬化、冠状动脉粥样硬化性心脏病、高血压病、血脂异常、血糖异常、心律失常等疾病方面疗效确切,临床应用温胆片时需辨清痰热内扰这一主要病机。其抗焦虑的作用机制可能与升高γ-氨基丁酸(GABA)含量及降低谷氨酸(Glu)含量有关,而其改善血管内皮功能机制则可能与提高血浆一氧化氮(NO)浓度及降低内皮素(ET)浓度有关。
In recent years, clinical efficacy and pharmacological studies of Wandan tablets treatment-related diseases are reviewed. Wenshen tablets from the warm gall soup cut from, with Qi and phlegm, clear gall and stomach, qi stagnation and other functions, has been widely used in clinical treatment of nervous system diseases, metabolic diseases and cardiovascular diseases, efficacy exact. In recent years, the literature on bile fever tablets shows that bile fever tablets in the treatment of generalized anxiety disorders, atherosclerosis, coronary heart disease, hypertension, dyslipidemia, abnormal blood glucose, arrhythmia and other diseases The curative effect is exact, the clinical application of bile sheet need to identify the main pathogenesis of phlegm heat disturbance. The mechanism of its anti-anxiety may be related to increasing the content of GABA and decreasing the content of glutamic acid (Glu), and its mechanism of improving vascular endothelial function may be related to the increase of plasma nitric oxide (NO) concentration and Lower endothelin (ET) concentration.