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慢性肾功能不全贫血中促红细胞生成素(EP)和红细胞生成受抑的重要性已作充分研究。作者采用血清EP测定和红系祖细胞(CFU-E)培养探索对于不同程度肾损害病人红系生成的影响因素。对象与方法:包括(1)不同病因的肾衰60例,均未经透析治疗,未用雄性激素,4例伴有肾疾患之外的贫血原因,包括2例消化性溃疡,1例镰状细胞贫血,1例多发性骨髓瘤;(2)正常人40例,血红蛋白值13.3-17.4g/dl,平均值15.7±0.17g/dl;(3)肾
The importance of inhibition of erythropoietin (EP) and erythropoiesis in chronic renal insufficiency anemia has been well studied. The authors used serum EP assay and erythroid progenitor cell (CFU-E) culture to explore the factors that influence erythroid formation in patients with varying degrees of renal impairment. Subjects and Methods: Including (1) 60 cases of renal failure of different etiologies, none of which were treated with androgen, 4 cases of anemia other than renal disease, including 2 cases of peptic ulcer, 1 case of sickle 1 case of multiple myeloma; (2) normal 40 cases, hemoglobin value 13.3-17.4g / dl, with an average of 15.7 ± 0.17g / dl; (3) kidney