α-diketones and β-diketones react with Grignard reagents in the presence of a catalytic amount of Cp2TiCl2 to yield α-ketols and corresponding ketones respe
A facile and highly diastereoselective method for the construction of 2-quaternary 1,3-amino alcohols and 1,3-diols has been developed on the basis of the AlEt3
5-Amino-3-methylthio-1H-pyrazoles are very important building blocks from which a wide variety of pyrazole de-rivatives can be prepared. When substituted 5-amin