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本文报告在斯里兰卡用复方新诺明片与氯霉素治疗伤寒和副伤寒的疗效比较。病例选择标准是住院成年病人,有发热和伤寒的临床表现,并有(1)血、血凝块或粪便培养伤寒或副伤寒菌阳性,或(2)伤寒病例“O”滴度递升,副伤寒病例的副伤寒甲“H”滴度升高伴有或不伴有“0”滴度升高。全部病例均随机分成两组。治疗前后都作血常规检查。两组的用药方法如下:(1)复方新诺明片组:2片(每片内含TMP 80mg和SMZ 400mg),每天2次,用至体温正常后7天。(2)氯霉素组:500mg,每6小时1次,用至退热后改为250mg,每
This article reports the efficacy of the combination of cotrimoxazole and chloramphenicol in the treatment of typhoid and paratyphoid in Sri Lanka. Case selection criteria were hospitalized adult patients with clinical manifestations of fever and typhoid fever and were (1) positive for typhoid or paratyphoid fever in blood, blood clots or faeces, or (2) elevated titer for “O” in typhoid fever, vice Paratuberculosis in typhoid fever “H” titers increased with or without “0” titers increased. All cases were randomly divided into two groups. Before and after treatment for blood tests. The two groups of drugs are as follows: (1) cotrimoxazole tablets group: 2 (each containing TMP 80mg and SMZ 400mg), 2 times daily until normal body temperature after 7 days. (2) chloramphenicol group: 500mg, every 6 hours 1, with antipyretic to 250mg, each