肺炎球菌性全身感染为肾病综合征患儿复发和死亡的主要原因。近代的研究表明,肾病综合征患儿严重感染的发病机制中,对细菌调理作用的缺乏与补体旁路途径的B因子血清浓度降低有关。为了预防这种感染,可应用多价肺炎球菌疫苗。肾病综合征患儿对肺炎球菌疫苗能产生一种血清学的免疫应答,但这种应答在这种疾病的复发期能否对肺炎球菌败血症提供相当程度的防卫作用仍不清楚。本文的病例,不论对 Pneumococcal systemic infection in children with nephrotic syndrome recurrence and death of the main reason. Modern research shows that the pathogenesis of severe infection in children with nephrotic syndrome, the lack of bacterial conditioning and complement bypass pathway factor B serum concentration decreased. To prevent this infection, a multivalent pneumococcal vaccine can be used. Children with nephrotic syndrome have a serological immune response to pneumococcal vaccine but it is unclear whether this response will provide a substantial degree of protection against pneumococcal sepsis in the relapse of this disease. This article’s case, no matter