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本文通过分析２６例抗中性粒细胞胞浆抗体（ＡＮＣＡ）阳性肾脏病例的临床病理特点，探讨了ＡＮＣＡ在肾脏病中的临床意义。结果显示，ＡＮＣＡ阳性不仅可见于结节性多动脉炎（４例）、紫癜性肾炎（８例），还可见于Ⅲ型新月体肾炎（２例）及ＩｇＡ肾病（１２例）．ＡＮＣＡ阳性的肾脏病例具有某些共同的临床病理特征，提示可能具有相同的发病机理。ＡＮＣＡ阳性的ＩｇＡ肾病及Ⅲ型新月体肾炎可能是特殊类型的血管炎。
In this paper, 26 cases of anti-neutrophil cytoplasmic antibody (ANCA) -related kidney cases of clinical and pathological features of ANCA in the clinical significance of kidney disease. The results showed that ANCA positive was not only found in polyarteritis nodosa (4 cases), purpuric nephritis (8 cases), but also in type III crescentic nephritis (2 cases) and IgA nephropathy (12 cases). ANCA positive kidney cases have some common clinical and pathological features, suggesting that may have the same pathogenesis. ANCA-positive IgA nephropathy and Crohn’s disease type III may be a special type of vasculitis.