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1 血脑屏障的组成与结构 血脑屏障(BBB)是中枢神经系统特有的结构。它的形态学基础包括血液与神经元之间的一系列结构:毛细血管的内皮及内皮细胞之间的闭锁小带、基膜以及神经胶质细胞突起(胶质膜)。以上结构使血脑屏障具有自身的特点:内皮细胞没有窗孔,大分子物质不易透过;内皮细胞之间有闭锁小带形成一完整的闭锁带,阻挡溶质透过;脑毛细血管内皮细胞缺少收缩性蛋白,脑毛细血管内皮没有特定的收缩能力,因此内皮对蛋
1 The composition and structure of the blood-brain barrier The blood-brain barrier (BBB) is a central nervous system-specific structure. Its morphological basis includes a series of structures between the blood and the neurons: a closed zonule between the endothelial and endothelial cells of the capillaries, the basement membrane, and the glial cell bulge (the glial membrane). The above structure enables the blood-brain barrier to have its own characteristics: endothelial cells do not have a window, macromolecules are not easily permeable; endothelial cells between the closure of a small band to form a complete blocking zone, blocking solute permeability; lack of brain capillary endothelial cells Contractile protein, brain capillary endothelial no specific ability to shrink, so the endothelium on the egg