钙化是动脉粥样硬化的一个显著特征 ,以往认为动脉钙化是动脉粥样硬化发生后的一个退行性过程 ,但是由于在钙化的动脉及瓣膜发现了作为羟基磷灰石发生中心的基质小泡 (ｍａｔｒｉｘｖｅｓｉｃｌｅｓ ,ＭＶＳ) ,以及一些骨相关蛋白 ,血管的钙化已被认为与骨组织钙化相似 ,是一个 Calcification is a prominent feature of atherosclerosis. In the past, arterial calcification was thought to be a degenerative process after atherosclerosis, but since matrix vesicles that are the center of hydroxyapatite are found in calcified arteries and valves matrixvesicles, MVS), as well as some bone-related proteins, vascular calcification has been considered similar to calcification of bone tissue, is a