Study on the Antibacterial Activity of Extracts from Wild Arctum Iappa L. Root

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[Objective]To study the antibacterial activity of different solvent extracts from wild Arctum lappa L.roots,so as to provide theoretical basis for its development and utilization.[Method]The method of minimum inhibitory concentration(MIC) and agar-well diffusion were adopted to determine the inhibitory activity of water and 70% ethanol extracts from burdock roots.[Result]Both extracts revealed the potential inhibitory activities against Escherichia coli,Proteus vulgaris,Bacillus subtilis and Staphylococcus aureus.A higher antimicrobial activity was observed in 70% ethanol extracts compared with water extracts,and the MIC to Bacillus subtilis and Staphylococcus aureus was 31.25 mg/ml,the MIC to Proteus vulgaris was 62.50 mg/ml,while that to Escherichia coli was 250 mg/ml;nevertheless,neither water extracts nor 70% ethanol extracts showed obvious antimicrobial effects on Saccharomyces erevisiae and Monilia albican.[Conclusion]The water and 70% ethanol extracts from Arctum lappa L.roots are endowed with good inhibitory effects on bacteria instead of yeasts,and 70% ethanol extracts are provided with better antimicrobial activity than water extracts. [Objective] To study the antibacterial activity of different solvent extracts from wild Arctum lappa L. roots, so as to provide theoretical basis for its development and utilization. [Method] The method of minimum inhibitory concentration (MIC) and agar-well diffusion were [Result] Both extracts revealed the potential inhibitory activities against Escherichia coli, Proteus vulgaris, Bacillus subtilis and Staphylococcus aureus. A higher antimicrobial activity was observed in 70% ethanol extracts compared with water extracts, and the MIC to Bacillus subtilis and Staphylococcus aureus was 31.25 mg / ml, the MIC to Proteus vulgaris was 62.50 mg / ml, while that to Escherichia coli was 250 mg / ml; % ethanol extracts illustrative obvious antimicrobial effects on Saccharomyces erevisiae and Monilia albican. [Conclusion] The water and 70% ethanol extracts from Arctum lappa L. roots a re endowed with good inhibitory effects on bacteria instead of yeasts, and 70% ethanol extracts are provided with better antimicrobial activity than water extracts.
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