妇女妊娠时其体内环境将发生一系列变化,其中直接或间接影响肝脏功能及胆红素代谢的因素有: 1.妊娠期内分泌改变卵巢及胎盘产生的激素增加,如黄体酮、孕二醇及其异构体等的增加,可减低葡萄糖醛酸基移换酶活力,阻碍肝细胞对胆红素的结合能力; 2.妊娠末期肝脏对胆红素的排泄能力 Women’s pregnancy when its body environment will occur a series of changes, which directly or indirectly affect the liver function and bilirubin metabolism factors: 1. Gestational endocrine changes in ovarian and placental hormone production, such as progesterone, pregnanediol and Its isomers and other increase, can reduce the glucuronosyl shift enzyme activity, hinder the binding capacity of liver cells to bilirubin; 2. The end of pregnancy liver bilirubin excretory capacity