表皮生长因子(EGF)广泛存在于体内众多组织中,尤以胃肠道为甚,它与特异受体结合而发挥作用,可促进DNA、RNA、蛋白质及多胺合成,刺激粘膜增生,上皮移行以及肉芽组织生长,并可增进谷氨酰胺对小肠粘膜的营养作用。此外,EGF还可促进双糖酶等的活性,改变质膜的流动性,从而影响葡萄糖等营养物的转运,以及Na~+—K~+,ATP酶活性,它在胃肠道组织的成熟,再生和修复,以及抗溃疡过程中起重要作用。 Epidermal growth factor (EGF) is widely found in many tissues of the body, especially in the gastrointestinal tract. It binds to specific receptors and plays a role in the synthesis of DNA, RNA, proteins and polyamines, and stimulates mucosal hyperplasia and epithelial migration As well as the growth of granulation tissue, and can enhance the nutrition of glutamine on the small intestine. In addition, EGF can also promote the activity of disaccharidase and change the fluidity of the plasma membrane, thereby affecting the transport of glucose and other nutrients, as well as Na ~ + -K ~ +, ATPase activity, its maturation in the gastrointestinal tract , Regeneration and repair, and anti-ulcer plays an important role.