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测定４６例Ⅱ型糖尿病患者（肾病２５例，非肾病２１例）和２４例正常人血清甲状旁腺激素（ＰＴＨ）、钙（Ｃａ）、磷（Ｐ）、碱性磷酸酶（ＡＫＰ）、肌酐（Ｃｒ）和尿白蛋白（Ａｌｂ），发现糖尿病患者血ＰＴＨ、ＡＫＰ和尿Ｐ浓度较正常人增高，血Ｃａ、Ｐ浓度较正常人降低，其中肾病患者ＰＴＨ值又较非肾病组增高，差异有显著性。相关分析示糖尿病肾病的ＰＴＨ值与血Ｃｒ、ＡＫＰ和尿Ｐ有较好的相关性。作者认为糖尿病患者存在钙、磷代谢异常，体钙缺乏，这种代谢异常在糖尿病肾病患者尤为明显，血清ＰＴＨ值、ＡＫＰ和尿Ｐ浓度是反映糖尿病肾病钙、磷代谢异常的有意义指标。
The serum levels of PTH, Ca, P, AKP and creatinine in 46 type Ⅱ diabetic patients (25 cases of nephropathy and 21 cases of non-nephropathy) and 24 cases of non-nephropathy were measured. (Cr) and urinary albumin (Alb). It was found that the blood levels of PTH, AKP and urinary P in blood of diabetic patients were higher than those in normal subjects, and the concentrations of blood Ca and P were lower than those in normal subjects. The PTH values in nephropathy patients were higher than those in non-nephropathy patients Significant. Correlation analysis showed that diabetic nephropathy PTH value and blood Cr, AKP and urine P have a good correlation. The authors believe that diabetic patients with abnormal calcium and phosphorus metabolism, body calcium deficiency, this metabolic abnormalities in patients with diabetic nephropathy is particularly evident, serum PTH value, AKP and urinary P concentrations reflect the diabetic nephropathy calcium and phosphorus metabolism abnormalities a meaningful indicator.