论文部分内容阅读
目的 观察糖尿病视网膜病变患者黄斑病变的光学相干断层扫描 (optical coherence tomo-graphy,OCT)图像特征。 方法 对 6 0例糖尿病黄斑病变患者以及 30例正常对照者进行 OCT检查。其中5 4例糖尿病黄斑病变患者同时行荧光素眼底血管造影 (fundus fluorescein angiography,FFA)检查 ,对两种检查方法的结果进行比较。 结果 OCT检查糖尿病黄斑病变患者中心凹平均厚度为 (314.5 4±15 4.13) μm。视网膜水肿者占 5 7.1% ,视网膜水肿合并黄斑囊样水肿 (cystoid macular edema,CME)者占38.5 % ,合并神经上皮脱离者占 9.2 % ,合并 CME及神经上皮脱离者占 16 .9%。OCT检查黄斑正常厚度及轻度水肿者 ,FFA主要呈限局性渗漏 ;中重度水肿者 ,FFA呈弥漫性渗漏。 CME检出率 FFA检查者为2 8.6 % ,OCT检查者为 5 8.9% ,二者比较差异有显著性意义 (t=3.39,P<0 .0 5 )。 结论 糖尿病黄斑病变者的 OCT图像有视网膜水肿、CME及神经上皮脱离 3种形态特征。 OCT在检测发现 CME等方面优于FFA。
Objective To observe the characteristics of optical coherence tomography (OCT) in macular degeneration in patients with diabetic retinopathy. Methods 60 patients with diabetic maculopathy and 30 normal controls were examined by OCT. 54 cases of diabetic macular degeneration patients underwent simultaneous fundus fluorescein angiography (FFA) examination, the results of the two methods were compared. Results The mean foveal thickness of patients with diabetic maculopathy by OCT was (314.5 4 ± 15 4.13) μm. Retinal edema accounted for 51.7%, retinal edema with cystoid macular edema (CME) accounted for 38.5%, combined with neuroepithelial detachment accounted for 9.2%, combined with CME and nerve epithelial detachment accounted for 16.9%. OCT examination macular normal thickness and mild edema, FFA mainly showed partial leakage; moderate to severe edema, FFA was diffuse leakage. The detection rate of CME was 28.6% for FFA and 59.9% for OCT, the difference was significant (t = 3.39, P <0.05). Conclusion OCT images of diabetic patients with macular degeneration have retinal edema, CME and neural epithelium detachment from three morphological characteristics. OCT is superior to FFA in detecting CME and other aspects.