论文部分内容阅读
目的探讨噻托溴铵联合肺康复措施对中、重度慢阻肺合并肺动脉高压患者的疗效。方法将71例临床缓解期的中、重度慢阻肺合并肺动脉高压患者分为观察组35例和对照组36例,对照组行肺康复措施6个月,观察组在此基础上接受噻托溴铵干粉吸入,比较两组患者6min步行距离、间接肺动脉收缩压、生活质量评分。结果观察组患者6min步行距离、间接肺动脉收缩压、生活质量评分方面优于对照组,差异有统计学意义(P<0.01)。结论噻托溴铵联合肺康复措施对稳定期中、重度慢阻肺合并肺动脉高压患者有明显效果,可增加患者舒适度,降低肺动脉压力、改善患者生活质量。
Objective To investigate the effect of tiotropium combined with pulmonary rehabilitation on moderate and severe COPD patients with pulmonary hypertension. Methods Seventy-one patients with moderate or severe chronic obstructive pulmonary disease (COPD) and pulmonary hypertension were divided into observation group (35 cases) and control group (36 cases). The control group received pulmonary rehabilitation for 6 months. The observation group received tiotropium Ammonia dry powder inhalation, compared with the two groups of patients walking distance 6min, indirect pulmonary artery systolic blood pressure, quality of life score. Results The observation group was superior to the control group in walking distance, indirect pulmonary artery systolic pressure, and quality of life score in 6min, with significant difference (P <0.01). Conclusion The combination of tiotropium and pulmonary rehabilitation has obvious effect on patients with moderate or severe chronic obstructive pulmonary disease and pulmonary hypertension, which can increase patient comfort, reduce pulmonary artery pressure and improve the quality of life of patients.