目的探讨肾病综合征合并低钠血症临床特征和治疗措施。方法回顾收治的46例肾病综合征合并低钠血症临床资料进行总结分析。结果经治疗45例症状在24～48h内纠正,血钠测定亦恢复正常钾、氯、钙恢复正常或基本正常,1例因合并低钾血症而死亡。结论正确的识别,积极的控制,能够减少和预防低钠血症发生,正确的治疗低钠血症能够得到良好的恢复。 Objective To investigate the clinical features and treatment of nephrotic syndrome with hyponatremia. Methods A retrospective analysis of 46 cases of nephrotic syndrome with hyponatremia clinical data were analyzed. Results After the treatment of 45 cases of symptoms corrected within 24 ~ 48h, serum sodium also returned to normal potassium, chloride, calcium returned to normal or almost normal, 1 case died of hypokalemia. Conclusions Proper identification and positive control can reduce and prevent the occurrence of hyponatremia. Correct treatment of hyponatremia can be well restored.