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小肝细胞癌往往伴有慢性肝病,因而有严重的肝损害,对伴有其他脏器损害的老年患者,手术切除多不可能。即使病灶比较局限,也很难根治。1982年作者首创超声波引导下穿刺经皮酒精注射法(percutane-ous ethanol injection therapy,PEI)治疗肿瘤直径<3cm的小肝细胞癌。在超声波引导下,用22G针穿刺进入肿瘤深部,选择1～2处注射99.5%酒精。用量根据肿瘤大小决定。一般2～6ml/次,2次/周,共4～6次。可随时改变针尖部位,使酒精浸润整个瘤体。注射量要充分,待超声波下见肿瘤形态完全改变时,方可停止注射。除有
Small hepatocellular carcinoma is often accompanied by chronic liver disease, resulting in severe liver damage. In elderly patients with other organ damage, surgical resection is not possible. Even if the lesion is more limited, it is difficult to cure. In 1982, the author’s first ultrasound-guided percutane-ous ethanol injection therapy (PEI) was used to treat small hepatocellular carcinoma with a tumor diameter of less than 3cm. Under ultrasound guidance, 22G needles were used to penetrate the deep part of the tumor, and 1 to 2 injections of 99.5% alcohol were selected. The dosage depends on the size of the tumor. Usually 2 ~ 6ml / time, 2 times / week, a total of 4 ~ 6 times. The needle tip can be changed at any time so that alcohol infiltrates the entire tumor. The amount of injection should be sufficient, until the complete change in the shape of the tumor under ultrasound, before stopping the injection. In addition to