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白血性网状内皮细胞增生症的发生率占白血病的2%。Bouroncle等于1958年首先报告本病26例,确定了本病的临床病理特征,认为是一种独立的疾病;并指出病人的血液中有一种网状细胞或组织细胞,这种细胞可伸出伪足,在胞浆膜周围,状似不规则的花边,在湿法及用电子显微镜观察特别清楚。数年以后Schrek等发现一种在细胞膜周围有大量绒毛的细胞,把它们称为毛细胞,故命名本病为毛细胞性白血病。目前已有许多毛细胞性白血病的病例报告以及用电子显微镜、细胞化学、功能和免疫学技术研究这种细胞的报告。
The incidence of leukemia reticuloendotheliosis accounts for 2% of leukemia. Bouroncle was first reported in 1958, 26 cases of the disease, to determine the clinicopathological features of the disease, that is an independent disease; and pointed out that the patient’s blood has a reticular cells or tissue cells, such cells can be extended pseudo Foot, around the cytoplasmic membrane, the shape of irregular lace, wet and electron microscopy is particularly clear. A few years later Schrek found a cell with a large amount of villi around the cells, called them hair cells, so named for the hair cell leukemia. There are many case reports of hairy cell leukemia and reports of such cells under electron microscopy, cytochemistry, functional and immunological techniques.