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目的:探讨丙戌酸钠治疗小儿癫痫的临床疗效。方法:选择我院2011年12月至2013年12月收治的癫痫患儿50例,随机分为两组,各25例。观察组患儿给予丙戌酸钠治疗,对照组患儿给予左乙拉西坦治疗;观察两组的临床疗效,并对比两组患儿治疗后出现的不良反应。结果:观察组总有效率为92.0%(23/25),对照组总有效率为80.0%(20/25),观察组显著高于对照组(P<0.05);观察组患儿不良反应发生率为8.0%(2/25),对照组患儿不良反应发生率为20.0%(5/25),观察组显著低于对照组(P<0.05)。结论:运用丙戌酸钠治疗小儿癫痫的效果明显优于左乙拉西坦,且并发症少,不良反应发生率低,有重要的临床使用价值。
Objective: To investigate the clinical efficacy of sodium propionate in the treatment of children with epilepsy. Methods: Fifty children with epilepsy who were admitted from December 2011 to December 2013 in our hospital were randomly divided into two groups (n = 25 each). Children in the observation group were treated with sodium propacrylate, while children in the control group were treated with levetiracetam. The clinical efficacy of the two groups was observed, and the adverse reactions were compared between the two groups. Results: The total effective rate was 92.0% (23/25) in the observation group and 80.0% (20/25) in the control group, which was significantly higher in the observation group than in the control group (P <0.05). The adverse reactions in the observation group The incidence of adverse reactions was 8.0% (2/25) in control group and 20.0% (5/25) in control group. The observation group was significantly lower than that of control group (P <0.05). CONCLUSION: The effect of sodium propacrylate on children with epilepsy is better than that of levetiracetam with less complications and low incidence of adverse reactions, which has important clinical value.