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目的:探讨米诺环素治疗非淋菌性宫颈炎的临床疗效及安全性。方法:将126例非淋菌性宫颈炎患者分为观察组(65例)和对照组(61例),观察组给予米诺环素治疗,对照组给予交沙毒素治疗,观察两组患者治疗疗效、病原体转阴率及不良反应情况。结果:观察组治疗总有效率为90.77%,明显高于对照组的55.74%(P<0.01);观察组病原体转阴率明显高于对照组(P<0.05);两组患者不良反应发生率比较无统计学差异(P>0.05)。结论:米诺环素治疗非淋菌性宫颈炎具有疗效好、病原体清除率高、不良反应少等优点。
Objective: To investigate the clinical efficacy and safety of minocycline in the treatment of non-gonococcal cervicitis. Methods: 126 cases of non-gonococcal cervicitis were divided into observation group (65 cases) and control group (61 cases). The observation group was treated with minocycline and the control group was treated with sand-toxin. The therapeutic effect was observed in both groups , Pathogen negative rate and adverse reactions. Results: The total effective rate in observation group was 90.77%, which was significantly higher than 55.74% in control group (P <0.01). The negative rate of pathogens in observation group was significantly higher than that in control group (P <0.05). The incidence of adverse reactions No statistical difference (P> 0.05). Conclusion: Minocycline is effective in treating non-gonococcal cervicitis, with high clearance rate of pathogens and few adverse reactions.