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流行性乙型脑炎(乙脑)是我国常见的一种以中枢神经系统损伤为主要特征的急性病毒性传染病,病死率高,后遗症重。儿童接种乙脑疫苗是预防乙脑的最有效手段。为评价乙脑灭活疫苗接种后的免疫血清学效果,我们对93名儿童接种了该疫苗,并在免疫前后检测了血清中和抗体,现将结果报告如下。1 材料和方法1·1 对象 在本市炮车和北沟两乡镇随机选择无免疫史的健康儿童93名,于免疫前、免疫后1个月分别采集静脉血,分高血清后检测血清乙脑中和抗体。1·2 疫苗 系卫生部上海生物制品研究所生产的灭活乙脑
Japanese encephalitis (JE) is a common acute viral infectious disease characterized by central nervous system injury in China. It has high mortality and severe sequelae. Children vaccinated with JE vaccine is the most effective means of preventing JE. To evaluate the immunological serological effects of JE inactivated vaccines, we vaccinated 93 children and detected serum neutralizing antibodies before and after immunization. The results are reported below. 1 Materials and methods 1.1 objects in the city gun and two townships randomly selected non-immune history of healthy children 93, before immunization, one month after the immunization were collected venous blood, divided into high serum serum B Brain neutralizing antibody. 1.2 Vaccine Department of Health Shanghai Institute of Biological Products inactivated JE