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肾病综合征在>60岁老年人中虽不常见,但在病因学诊断和甾类化合物药物的使用方面尚存在很大的盲目性。本文对诊为肾病综合征的59～83岁(平均69.3岁)老年患者,进行肾活组织检查及生化、肾功能及免疫学检查,并对其组织学分类、临床演化过程及治疗进行了观察。结果共30例(男24,女6)接受了检查。在组织学诊断方面,以膜性肾小球病(MGN)最常见,共7例,内1例在诊断肾病综合征后1年发生肺癌。膜增生性肾小球肾病(MPGN)次之,共6例,其中2例分别继发于冷球蛋白血症和多发性骨髓瘤,1例与急性克雷杆菌肺炎有关,另一例既往有结核和甲状腺
Nephrotic syndrome is uncommon in> 60-year-olds, but there is a great deal of blindness in the etiology of diagnoses and in the use of steroid drugs. In this paper, renal biopsy, renal function and immunological examination of 59-83 years old (average 69.3 years) old patients diagnosed with nephrotic syndrome were performed. The histological classification, clinical evolution and treatment were also observed . Results A total of 30 cases (male 24, female 6) were examined. In histological diagnosis, the most common membranous glomerulonephritis (MGN), a total of 7 cases, 1 case of diagnosis of nephrotic syndrome in 1 year after lung cancer. Membranous proliferative glomerulonephritis (MPGN) followed by a total of 6 cases, of which 2 cases were secondary to cryoglobulinemia and multiple myeloma, 1 case of acute Klebsiella pneumoniae related to the other with the previous case of tuberculosis And thyroid