目的分析安徽省合肥市知识分子人群冠心病(CHD)的患病情况及主要危险因素,为冠心病防治提供依据。方法采用整群抽样方法,对合肥市4726名35岁以上知识分子进行冠心病患病情况调查。比较不同年龄、性别的冠心病患病率,同时进行相关危险因素Logistic回归分析。结果调查对象中共检出冠心病患者265例,患病率为5.6%;其中男性为5.1%,女性为6.9%,女性高于男性(χ2=6.126,P<0.05);男女性患病率均随年龄增长呈增加趋势,男性χ2=149.056,P<0.001;女性χ2=111.099,P<0.001)。多因素分析显示,冠心病的主要危险因素为年龄(OR=3.627,95%CI=2.905~4.529,P=0.000)、性别(OR=0.692,95%CI=0.501~0.955,P=0.025)、冠心病家族史(OR=2.347,95%CI=1.656~3.327,P=0.000)、高血压(OR=1.537,95%CI=1.144~2.064,P=0.004)、腰臀比(OR=1.463,95%CI=1.091~1.961,P=0.011)、食盐摄入(OR=1.236,95%CI=1.009~1.516,P=0.041)。结论合肥市知识分子人群冠心病患病率较高,应作为冠心病高危人群进行干预预防。 Objective To analyze the prevalence and risk factors of coronary heart disease (CHD) among the intellectuals in Hefei, Anhui Province, and provide evidence for the prevention and treatment of coronary heart disease. Methods A cluster sampling method was used to investigate the prevalence of coronary heart disease among 4726 intellectuals over the age of 35 in Hefei City. The prevalence of coronary heart disease was compared with different age and sex, and Logistic regression analysis was performed on related risk factors. Results There were 265 cases of CHD detected in the survey subjects, with a prevalence of 5.6%. Among them, 5.1% were male, 6.9% were female, and were higher in women than in men (χ2 = 6.126, P <0.05) With increasing age, male χ2 = 149.056, P <0.001; female χ2 = 111.099, P <0.001). Multivariate analysis showed that the main risk factors for coronary heart disease were age (OR = 3.627, 95% CI = 2.905-4.529, P = 0.000), sex (OR = 0.692, 95% CI = 0.501-0.95 5, P = 0.025) (OR = 2.347, 95% CI = 1.656-3.327, P = 0.000), hypertension (OR = 1.537, 95% CI = 1.144-2.064, P = 0.004) 95% CI = 1.091-1.961, P = 0.011), salt intake (OR = 1.236, 95% CI = 1.009-1.516, P = 0.041). Conclusion The prevalence of coronary heart disease is higher in the population of intellectuals in Hefei City, and should be used as a preventive measure for people at high risk of coronary heart disease.