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狼疮肾炎 (ＬＮ)是系统性红斑狼疮 (ＳＬＥ)患者死亡的主要原因之一。ＳＬＥ患者中约有 5 0 %～ 80 %可出现肾炎性改变 ,几乎全部出现肾损害[1 ] 。因此 ,ＬＮ的早期及有效治疗 ,已成为ＳＬＥ治疗中的关键环节。环磷酰胺 (ＣＴＸ)是目前治疗ＬＮ过程中应用较多的药物之一 ,我们
Lupus nephritis (LN) is one of the major causes of death in patients with systemic lupus erythematosus (SLE). SLE patients, about 50% to 80% of renal inflammatory changes can occur, almost all renal damage [1]. Therefore, the early and effective treatment of LN has become a key link in the treatment of SLE. Cyclophosphamide (CTX) is one of the most widely used drugs in the treatment of LN