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目的分析ICU发生呼吸机相关性肺炎(VAP)的危险因素,以期为VAP的预防提供参考。方法回顾性分析2008年1月—2011年6月我院ICU行人工机械通气患者300例的相关临床资料,采用多因素Logistic回归分析分析患者发生VAP的危险因素。结果 80例患者发生VAP,发生率为26.67%。Logistic回归分析结果显示,误吸、机械通气时间>3 d、抗生素联用是发生VAP的危险因素(P值分别为0.032、0.033、0.015)。结论 ICU发生VAP的危险因素为误吸、机械通气时间>3 d及抗生素联用。
Objective To analyze the risk factors of ventilator associated pneumonia (VAP) in ICU in order to provide a reference for the prevention of VAP. Methods The clinical data of 300 patients with ICU in our hospital from January 2008 to June 2011 were retrospectively analyzed. Multivariate Logistic regression analysis was used to analyze the risk factors of VAP in patients. Results 80 cases of patients with VAP, the incidence was 26.67%. Logistic regression analysis showed that aspiration and mechanical ventilation for more than 3 days, combination of antibiotics was a risk factor for VAP (P = 0.032, 0.033, 0.015, respectively). Conclusions The risk factors of VAP in ICU are aspiration, mechanical ventilation> 3 days and antibiotics combined.