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目的观察应用CAG方案治疗老年急性髓细胞白血病的疗效。方法回顾性分析我院2008年1月至2011年1月应用CAG方案治疗老年急性髓细胞白血病的临床资料。结果全部患者均顺利完成治疗,总有效率达71.8%(5+4+14/32)。化疗后的主要不良反应为骨髓抑制,8例患者出现发热,经抗生素和/或抗真菌治疗后体温逐渐恢复正常,5例皮肤出现出血点,消化道反应轻微,经对症处理后上述症状及生化指标均恢复正常,无明显的肝肾功能损害。结论应用CAG方案治疗老年急性髓细胞白血病有效率高,不良反应少,适合临床推广和应用。
Objective To observe the effect of CAG regimen in the treatment of senile acute myeloid leukemia. Methods A retrospective analysis of our hospital from January 2008 to January 2011 CAG regimen in the treatment of elderly patients with acute myeloid leukemia clinical data. Results All patients were successfully treated, with a total effective rate of 71.8% (5 + 4 + 14/32). The main adverse reaction after chemotherapy was myelosuppression. Eight patients had fever. The body temperature gradually returned to normal after antibiotic and / or antifungal treatment. Bleeding points occurred in 5 cases of skin and the digestive tract reaction was mild. After symptomatic treatment, the above symptoms and biochemistry Indicators returned to normal, no significant liver and kidney dysfunction. Conclusion The CAG regimen is effective in treating elderly patients with acute myeloid leukemia with few adverse reactions and is suitable for clinical application and promotion.