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本文主要对93例多系统器官功能衰竭(MSOF)患儿进行了临床分析,阐明了衰竭器官数目与病死率成正比。分析了 MSOF 的直接致衰因素与潜在致衰因素。通过25例 MSOF 患儿外周微循环的动态现察,发现所测微循环指标中的8项,MSOF 期较肺炎恢复期明显异常,差异非常显著(P<0.01)。表现为管袢严重痉挛及部分关闭,血流缓慢,中重度红细胞聚集。晚期可见管袢迂曲扩张。提示小儿肺炎并发 MSOF 始终贯穿着以肺微循环障碍为主的全身性微循环障碍。
In this paper, 93 cases of multi-system organ failure (MSOF) were analyzed clinically, and the number of failing organs was directly proportional to the case fatality rate. Analyzed the MSOF direct cause of decline and potential causes of deterioration factors. Through the dynamic observation of peripheral microcirculation in 25 cases of MSOF children, it was found that 8 of the measured microcirculation indexes were significantly abnormal (P <0.01). Manifested as severe spasm tube and partial closure, slow blood flow, moderate to severe red blood cell aggregation. Late tube 袢 tortuous expansion. Prompt pediatric pneumonia complicated MSOF always runs through the systemic microcirculation disorder with pulmonary microcirculation.