目的：探讨中线恶网的诊断及其临床病理意义，与其他一些疾病的鉴别诊断。方法：对中线恶网进行临床病理分析和免疫表型标记。结果：５０例中线恶网中，Ｔ细胞淋巴瘤４３例，Ｂ细胞淋巴瘤２例，余５例尚不能分类。结论：结果表明本病多数是Ｔ细胞淋巴瘤（即所谓的中线Ｔ淋巴瘤）。认为本病的临床、病理特点结合免疫标记技术有助于中线Ｔ淋巴瘤的确诊。 Objective: To investigate the diagnosis and clinicopathological significance of midline malignancies and differential diagnosis with other diseases. Methods: Clinical pathological analysis and immunophenotypic markers were performed on the midline evil network. RESULTS: Of the 50 cases of midline malignancies, 43 were T-cell lymphomas, 2 were B-cell lymphomas, and the remaining 5 were not classified. Conclusion: The results showed that the majority of the disease is T-cell lymphoma (so-called midline T-lymphoma). It is believed that the clinical and pathological features of this disease combined with immunolabeling techniques are helpful for definitive diagnosis of midline T-lymphoma.