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本文运用世界卫生组织推荐的神经行为核心测试组合对23名接触二硫化碳的男性作业工人及年龄、文化程度和生活习惯与接触组相近的29名对照工人的神经行为功能进行测试。结果表明:作业工人在接触平均CS2浓度为12~55mg/m3、尿TTCA水平在0.953mg/g·肌酐的情况下,4项神经行为测试(数据广度、视觉保留、数字译码和目标追踪)的得分显著低于对照组。进一步采用多元回归分析的方法调整年龄、文化程度对神经行为功能的影响,结果发现,数字译码测试项与接触工作环境CS2浓度呈负相关,而目标追踪测试项与工人尿TTCA水平呈负相关,提示长期高浓度接触CS2可影响作业工人的感知速度功能,而短期高浓度接触CS2影响精细操作控制和感知速度功能。
In this study, we tested the neurobehavioral function of 23 male workers exposed to carbon disulfide and 29 control workers with similar age, education, and living habits to the exposure group, using the core behavioral core test set recommended by the World Health Organization. The results showed that there were 4 neurobehavioral tests (data breadth, visual preservation, digital decoding and target tracking) with working-class workers exposed to mean CS2 concentrations of 12-55 mg / m3 and urinary TTCA levels of 0.953 mg / ) Score was significantly lower than the control group. Furthermore, using multiple regression analysis to adjust the effect of age and education level on neurobehavioral function, we found that there is a negative correlation between digital decoding test items and exposure to working environment CS2 concentration, while the target tracking test items are negatively correlated with urine TTCA level , Suggesting that long-term high-level exposure to CS2 may affect workers’ perceived speed function, whereas short-term high-concentration exposure to CS2 affects fine operation control and sensory speed function.