论文部分内容阅读
目的探讨影响尘肺病患者生存年限的因素。方法以尘肺患者的死亡风险函数为应变量,生存年限为暴露时间变量,发病工龄、工种、是否并发肺结核、Ⅱ期晋升为Ⅲ期的年限及尘肺种类为方程自变量,运用STATA统计分析软件进行尘肺病例生存年限的COX比例风险模型分析。结果COX比例风险模型方程为:λ(t)=λ_0(t)exp(-0.0249×fb+0.0344×gz+0.2059×tb-0.0215×nx_2- 0.0280×cf),矽肺相对于煤工尘肺的COX比例风险模型方程为:λ(t)=λ_0(t)exp(0.5289×cf)。由COX模型方程可得出各自变量的相对危险度(RR)值分别为1.025、1.035、1.229、1.022、1.697.提示,发病工龄对患者死亡的影响呈递减的形式,发病工龄每减少1年,尘肺病例在某时刻死亡的RR增加1.025倍;井下采矿工尘肺病例在某时刻死亡的RR值是非井下采矿工尘肺病例的1.035倍;尘肺并发肺结核在某时刻死亡的RR值是单纯尘肺的1.229倍;Ⅱ期尘肺晋升为Ⅲ期的年限每减少1年,尘肺病例在某时刻死亡的RR值增加1.022倍;矽肺病例在某时刻死亡的RR值是煤工尘肺的1.697倍。结论影响尘肺病例生存年限的因素有发病工龄、工种、是否并发肺结核、Ⅱ期尘肺晋升为Ⅲ期的年限及尘肺种类。
Objective To explore the factors affecting the life span of patients with pneumoconiosis. Methods According to the risk of death in patients with pneumoconiosis as the dependent variable, the survival time was the time variable of exposure, the age of onset of the disease, the type of work, whether complicated with pulmonary tuberculosis, the duration of phase Ⅱ to phase Ⅲ and the type of pneumoconiosis as the independent variables, using STATA statistical analysis software COX Proportional Hazard Analysis of Survival of Pneumoconiosis Cases. Results COX proportional hazards model equation is as follows: λ (t) = λ_0 (t) exp (-0.0249 × fb + 0.0344 × gz + 0.2059 × tb- 0.0215 × nx_2- 0.0280 × cf). The COX ratio of silicosis to coal worker’s pneumoconiosis The risk model equation is: λ (t) = λ_0 (t) exp (0.5289 × cf). The relative risk (RR) values of the respective variables were 1.025,1.035,1.229,1.022,1.697 respectively from the COX model equation, suggesting that the impact of the length of service on the patient’s death showed a decreasing form, The RR of death in pneumoconiosis cases increased by 1.025 times. The RR of death of underground miners in a certain time was 1.035 times of that of non-underground miners. The RR of death from pneumoconiosis complicated with pulmonary tuberculosis was 1.229 times that of simple pneumoconiosis ; For stage II pneumoconiosis, the RR of death from pneumoconiosis increased by 1.022 times for every 1-year reduction; the RR of death from silicosis was 1.697 times of that for coal worker’s pneumoconiosis. Conclusion The factors influencing the life span of patients with pneumoconiosis are length of service, type of work, pulmonary tuberculosis complicated or not, stage Ⅱ pneumoconiosis to stage Ⅲ and type of pneumoconiosis.