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目的:观察对比替硝唑四联治疗幽门杆菌复发性溃疡的临床疗效。方法:选择143例幽门杆菌反复性溃疡患者为研究对象,随机分为实验组与对照组,实验组应用替硝唑四联治疗方案进行治疗,对照组不予以抗Hp治疗,对比分析两组疗效。结果:在治疗过程中,实验组患者出现4例毒副作用,对照组出现1例,两组相比较差异不存在统计学意义(P﹥0.05),治疗中出现的毒副作用均能耐受。结论:替硝唑四联对幽门杆菌复发性溃疡有较好的治疗效果。
Objective: To observe the clinical efficacy of tinidazole quadruple in the treatment of recurrent Helicobacter pylori ulcer. Methods: 143 cases of H.pylori ulcer patients were randomly divided into experimental group and control group. The experimental group was treated with tinidazole quadruple-therapy regimen, while the control group was not given anti-Hp treatment. The curative effect of the two groups were compared . Results: During the course of treatment, there were 4 cases of side effects in the experimental group and 1 case in the control group. There was no significant difference between the two groups (P> 0.05). All the toxic and side effects in the treatment group were tolerable. Conclusion: Tinidazole quadruple recurrent ulcer with H. pylori has a better therapeutic effect.