非类固醇抗炎药物(NSAIDs)广泛应用于临床,由此引起的胃、十二指肠损害越来越受到人们的关注。我们的研究包括溃疡出血组、消化性溃疡组、住院病人组、健康人组,结果示消化性溃疡组服用NSAIDs明显高于其他组,特别是十二指肠溃疡病人,多数病人在出血前有服NSAIDs历史,且药物频率大于其它组。部分服用NSAIDs病人以出血为首发症状,扑热息痛对消化溃疡出血并无影响。 Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in clinic, and the gastric and duodenal damage caused by them are getting more and more attention. Our study included ulcer bleeding group, peptic ulcer group, hospitalized patients group, healthy people group, the results showed that peptic ulcer group taking NSAIDs was significantly higher than other groups, especially duodenal ulcer patients, most patients before the bleeding NSAIDs history of service, and the drug frequency is greater than other groups. Some patients taking NSAIDs bleeding as the first symptom, paracetamol has no effect on the digestive ulcer bleeding.