论文部分内容阅读
治疗快速性心律失常传统上是应用药物。这一类药物种类很多,而且近年发展很快。过去根据其药理作用分类。自从对心肌细胞电生理进行深入研究,提出了心律失常的细胞膜内外离子转运学说以后,抗快速性心律失常药物趋向于按其细胞电生理作用来分类。目前最常用的分类法是Vaughan Williams在1971年提出,1979年经Harrison修订的分类法。这一分类法将本类药物分为:Ⅰ类膜稳定剂、Ⅱ类β阻滞剂、Ⅲ类复极抑制剂、Ⅳ类钙拮抗剂。其中Ⅰ类又主要按其对JT间期的作用是延长、不变或基本不变分为Ia、Ib、Ic三个亚组。Ia组药以奎尼丁、普鲁卡
Therapies for tachyarrhythmia are traditionally used drugs. There are many types of drugs in this category, and have developed rapidly in recent years. Past the classification according to their pharmacological effects. Since the electrophysiological studies of cardiomyocytes have been carried out and the theory of ion transport inside and outside the cell membrane of arrhythmia has been proposed, anti-tachyarrhythmia drugs tend to be classified according to the electrophysiological effects of their cells. The most commonly used taxonomy today is the taxonomy that Vaughan Williams proposed in 1971 and revised in Harrison in 1979. This classification will be divided into the class of drugs: Ⅰ class membrane stabilizer, β blockers Ⅱ, Ⅲ class repolarization inhibitors, Ⅳ class of calcium antagonists. Among them, Class I mainly depends on its role in the JT interval is extended, unchanged or basically unchanged into three sub-groups Ia, Ib, Ic. Group Ia quinidine drugs, procaine