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对江苏省1996年~1999年817例急性弛缓性麻痹(AFP)病例进行了检测,分离出病毒152株,阳性分离率为18.60%,其中脊髓灰质炎(简称脊灰)病毒40株,分离率为4.90%,用PCR-RFLP分析法鉴定其型内待征,均为疫苗株。分离到非脊灰肠道病毒(NPEV)112株,分离率为13.70%,不同月份分离率不同,以夏季为高。不同年龄组,不同采便时间、不同地区间NPEV分离率无显著性差异。NPEV分离率达到了世界卫生组织(WHO)推荐的非脊灰肠道病毒分离率标准(10%),AFP病例中存在3个血清型,全部为脊灰疫苗株,表明我省脊灰实验室监测系统是敏感的。
152 cases of acute flaccid paralysis (AFP) were detected in 817 cases of AFP from 1996 to 1999 in Jiangsu Province. The positive rate of isolation was 18.60%, of which 40 were poliomyelitis (polio) The isolation rate was 4.90%. The PCR-RFLP analysis was used to identify the type of vaccine, and all were vaccine strains. One hundred and twelve isolates of non-polio enterovirus (NPEV) were isolated with the isolation rate of 13.70%. The separation rates were different in different months and were higher in summer. There was no significant difference in NPEV isolation rate among different age groups, different feces sampling times and different regions. NPEV isolation rate reached the World Health Organization (WHO) recommended isolation rate of non-polio enterovirus (10%), AFP cases there are three serotypes, all polio vaccine strains, indicating that our province polio laboratory Monitoring system is sensitive.