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[目的]比较肺癌放疗中采取同层扫描及三相扫描时肿瘤靶区(GTV)体积、前后径、左右径、上下径及剂量体积直方图中双肺受量指标的差异。[方法]选取行放疗的肺癌患者10例,依次完成三相扫描及同层扫描,在相同的窗宽窗位上以相同的标准勾画靶区,将三相扫描获得的3套CT片中勾画的靶区融合后定义为GTV3x,将同层扫描获得的8套CT片中勾画的靶区融合后定义为GTV8x,分别制定Plan3x和Plan8x,比较GTV3x和GTV8x的体积、前后径、左右径、上下径及Plan3x和Plan8x双肺V5、V10、V20、V30的差别。[结果]两组相比,左右径、前后径无明显统计学差异(P值分别为0.167和0.575),体积、上下径有统计学差异(P值分别为0.005和0.001)。V5、、V10、V20、V30、MLD均有统计学差异(P值分别为0.003、0.005、0.000、0.002和0.000)。[结论]同层扫描相对于三相扫描,可降低双肺受量V5、V20、V30,在减轻放疗并发症、提高患者生活质量方面有优势。
[Objective] To compare the difference of the volume of lung volume, anteroposterior diameter, left and right diameter, up and down diameter and volume-volume histogram of lung volume in the same layer scan and three-phase scan in radiotherapy of lung cancer. [Methods] Ten patients with lung cancer undergoing radiotherapy were selected. Three-phase and one-layer scans were performed sequentially. The same window and window were used to outline the target area. Three sets of CT images obtained by three-phase scanning were sketched Of the target area fusion defined as GTV3x, 8 sets of CT slices scored in the same layer were fused and defined as GTV8x, respectively Plan3x and Plan8x, compare GTV3x and GTV8x volume, anteroposterior diameter, left and right diameter, up and down Path and Plan3x and Plan8x lung V5, V10, V20, V30 differences. [Results] There was no significant difference in left and right diameter and anteroposterior diameter between the two groups (P = 0.167 and 0.575, respectively). There was a statistically significant difference in volume and up and down diameter (P = 0.005 and 0.001 respectively). V5, V10, V20, V30, MLD were statistically significant (P values were 0.003,0.005,0.000,0.002 and 0.000). [Conclusion] Compared with three-phase scanning, the same-layer scanning can reduce the volume of bilateral lung V5, V20, V30, which has the advantages of reducing the complications of radiotherapy and improving the quality of life of patients.