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甲状腺癌肿瘤标志物是由甲状腺癌组织和细胞产生的异常表达的生物活性物质。近年来,肿瘤标志物成为肿瘤基础和临床应用的一个非常活跃的领域,其不仅与甲状腺癌的形成、发展和转移关系密切,也对它的诊断和治疗具有重要意义。随着研究的不断深入,这些肿瘤标志物在临床上已显示出了广阔的应用前景。本文就近年来研究较多且与甲状腺癌密切相关的肿瘤标志物,包括Galectin-3,CK-19,VEGF,端粒酶和端粒酶逆转录酶,MMPs,降钙素,E-cadherin,Tg,TSHRmRNA进行综述。
Thyroid cancer tumor markers are abnormally expressed bioactive substances produced by thyroid cancer tissues and cells. In recent years, tumor markers have become a very active field of tumor basic and clinical applications. They are not only closely related to the formation, development and metastasis of thyroid cancer, but also have great significance for its diagnosis and treatment. With the deepening of research, these tumor markers have shown a broad application prospect in clinic. In this paper, in recent years, more and more closely related to thyroid cancer tumor markers, including Galectin-3, CK-19, VEGF, telomerase and telomerase reverse transcriptase, MMPs, calcitonin, E-cadherin, Tg , TSHR mRNA are reviewed.