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Morgan(1976)等在用植物凝血素(PHA)刺激的淋巴细胞的培养上清液中,发现了选择地使T 细胞增殖,并能长期传代培养的淋巴因子。此淋巴因子在“国际淋巴因子学术讨论会(1979)”上被命名为白间素—2(interleukin,IL—2),现正在对其免疫反应机制进行研究。同时,已作为一种免疫增强剂通过各种方法试用于临床。研究结果表明,产生IL—2的细胞有T 细胞、NK细胞等。本实验中作者比较观察了喉癌患者和正常人的末梢血淋巴细胞转化率及由同种淋巴细胞产生IL—2的
In the culture supernatant of lymphocytes stimulated with phytohemagglutinin (PHA), Morgan et al. (1976) found that lymphocytes selectively proliferate T-cells and can be subcultured for a long time. This lymphokine was named interleukin-2 (IL-2) at the International Symposium on Lymphokine (1979), and its immune response mechanism is under investigation. At the same time, it has been tried out clinically by various methods as an immune enhancer. The results show that IL-2-producing cells have T cells, NK cells and so on. In this study, the authors compared the rate of peripheral blood lymphocyte transformation in patients with laryngeal cancer and normal and IL-2 production by allogeneic lymphocytes