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光动力学疗法已用于许多肿瘤的治疗,如复发性乳腺癌、头颈部鳞癌、支气管肺癌、胃肠道癌、膀胱癌。据报告,支气管肺癌和胃肠道癌的完全或部分缓解率达60%以上。亦有报告用其治疗食管癌。作者对14例食管癌患者行Ⅰ期研究。全部病例激光治疗前72小时静脉滴注血卟啉衍生物(HPD)2.5～5.0mg/kg,屏蔽直接日光照射l个月以上,作者用能产生激光627～630urn的氩离子驱动若丹明染料
Photodynamic therapy has been used in the treatment of many cancers, such as recurrent breast cancer, head and neck squamous cell carcinoma, bronchial lung cancer, gastrointestinal cancer, and bladder cancer. According to reports, the complete or partial remission rate of bronchial lung cancer and gastrointestinal cancer is over 60%. It has also been reported to treat esophageal cancer. The authors conducted a phase I study of 14 patients with esophageal cancer. In all cases 72 hours before laser treatment, intravenous infusion of hematoporphyrin derivative (HPD) 2.5-5.0mg/kg, shielded from direct sunlight for more than 1 month, the author used argon ions capable of generating laser 627-630urn to drive rhodamine dye