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尸解资料证实,系统性红斑狼疮(SLE)心肌炎的发生率高达40%～70%,但是临床出现心功能失调表现的发生率仅为5%～10%。诊断这类心肌损害需要使用精细的方法。临床上左室舒张功能失调的出现通常先于收缩功能的失调。为此,作者在一组没有心功能失调表现和超声检查亦未见左室收缩功能异常的 SLE 病人中,应用 Doppler 超声检查测定左室舒张功能的变化,探讨 SLE 病人左室舒张功能失调的发生率和舒张功能与疾病活动之间的关系。病人和方法 35例符合美国风湿协会诊断的 SLE 病人,男6例,女29例,年龄22～84(平均41)岁,病程0.1～23(平均7.1)年,其中
Autopsy data confirm that the incidence of systemic lupus erythematosus (SLE) myocarditis as high as 40% to 70%, but the incidence of clinical manifestations of cardiac dysfunction is only 5% to 10%. Diagnosis of such myocardial damage requires the use of sophisticated methods. Clinical manifestations of left ventricular diastolic dysfunction usually precede the dysfunction of systolic function. To this end, the authors in a group of patients without heart failure and ultrasound examination showed no abnormal left ventricular systolic function in patients with SLE, the application of Doppler ultrasound examination of left ventricular diastolic function changes to explore the SLE patients with left ventricular diastolic dysfunction occurred The relationship between rate and diastolic function and disease activity. Patients and Methods 35 patients with SLE diagnosed by American Society of Rheumatology included 6 males and 29 females, ranging in age from 22 to 84 (average 41 years) with a duration of 0.1 to 23 (average 7.1 years), of which,