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目的探讨原发性十二指肠恶性肿瘤临床治疗和诊断方法。方法分析在2000年1月~2014年1月本院确诊收治的63例原发性十二指肠恶性肿瘤患者的临床资料,根据患者的不同手术方式分析治疗效果。结果原发性十二指肠恶性肿瘤临床症状表现为上腹阵痛、餐后阵发性疼痛、恶心、呕吐等。十二指肠镜和CT镜确诊的正确率分别为86.4%和45.3%。采用十二指肠直接切除手术的术后存活率高于局部节段或肿瘤切除手术。结论采用十二指肠直接切除手术是治疗原发性十二指肠恶性肿瘤的首选方法。
Objective To investigate the clinical treatment and diagnosis of primary duodenal malignancies. Methods Clinical data of 63 patients with primary duodenal malignancy diagnosed in our hospital from January 2000 to January 2014 were analyzed. The therapeutic effect was analyzed according to the patients’ different surgical methods. Results The clinical manifestations of primary duodenal malignancies were asymptomatic pain, postprandial paroxysmal pain, nausea and vomiting. The correct rates of diagnosis of duodenoscopy and CT were 86.4% and 45.3% respectively. Postoperative survival of the direct duodenal resection was higher than that of the local segment or tumor resection. Conclusion The direct operation of duodenal resection is the preferred method for the treatment of primary duodenal malignancies.