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目的:对豁痰清窍解郁汤、草酸艾司西酞普兰片口服及综合康复治疗卒中后抑郁患者的临床效果进行对比与分析。方法:本组研究对象来源于医院收治的128例卒中后抑郁患者,根据掷骰子法随机分为实验组和对照组,每组64例患者。对照组患者给予草酸艾司西酞普兰片口服及综合康复治疗,实验组患者给予豁痰清窍解郁汤、草酸艾司西酞普兰片口服及综合康复治疗。对比两组患者的生活质量评分情况、HAMD评分情况及Zung评分情况。结果:实验组患者经治疗后的生活质量评分、HAMD评分情况(9.25±0.26)分及Zung评分情况(50.10±3.22)分明显优于对照组生活质量评分、HAMD评分情况(16.96±0.68)分及Zung评分情况(64.25±9.89)分,其差异统计学上有意义(P<0.05)。结论:应用豁痰清窍解郁汤、草酸艾司西酞普兰片口服及综合康复治疗对卒中后抑郁患者进行系统治疗,能够有效缓解患者焦虑情绪,患者生活质量有明显提高,但远期的临床效果仍然需要通过延长随访时间和加大样本量来进行证实。
OBJECTIVE: To compare and analyze the clinical efficacy of Phlegm-Resolving and Clearing-Essence Jie Decoction and escitalopram oxalate tablets in oral and comprehensive rehabilitation of patients with post-stroke depression. Methods: The subjects in this study were 128 patients with post-stroke depression who were admitted to the hospital. They were randomly divided into experimental group and control group according to the method of rolling dice, with 64 patients in each group. Patients in the control group were treated with escitalopram oxalate orally and comprehensively. Patients in the experimental group were treated with Phlegm-Resolving Qifeng Jieyu Decoction and escitalopram oxalate in oral and comprehensive rehabilitation. Quality of life scores, HAMD scores and Zung scores were compared between the two groups. Results: The quality of life score, HAMD score (9.25 ± 0.26), Zung score (50.10 ± 3.22) in the experimental group were significantly better than those in the control group, and the HAMD score was (16.96 ± 0.68) points And Zung scores (64.25 ± 9.89), the difference was statistically significant (P <0.05). Conclusions: Phoexist qi-qi soup and escitalopram oral and comprehensive rehabilitation treatment of post-stroke depression in patients with systemic treatment, can effectively relieve anxiety in patients with patients with significantly improved quality of life, but the long-term The clinical effect still needs to be confirmed by extending the follow-up time and increasing the sample size.