采用细胞消化传代同时加疫苗病毒感染细胞的方法 (简称同时感染法 )与细胞长成单层后再加病毒感染细胞的方法 (简称单层感染法 )所制备的疫苗进行质量比较 ,结果同时感染法的生产周期明显缩短 ,病毒达增殖高峰期的细胞仍能保持良好的形态 ,疫苗病毒滴度明显提高。表明该工艺更适合于规模化、工业化生产 Using cell digestion passage at the same time plus vaccine virus infected cells method (referred to as simultaneous infection method) and the cells grow into a monolayer after adding virus-infected cells (hereinafter referred to as monolayer infection method) prepared vaccine quality comparison results as a result of infection France’s production cycle was significantly shortened, the virus reached the peak proliferation of cells can still maintain a good shape, the vaccine virus titer was significantly improved. Show that the process is more suitable for large-scale, industrial production