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对从白眉蝮蛇毒、江浙蝮蛇毒和尖吻蝮蛇毒中提取的蛇毒抗栓酶制剂进行了酶活性和安全性分析。被检样品的精氨酸酯酶活性都能达到要求，有的还超过出厂规格的1～3倍，但类凝血酶活性定性试验只有68.1％（64／94批）呈阳性反应。出血毒性和神经毒性检测，有14．4％和38．5％的样品不能通过。用SDS－PAGE分析纯度，被检样品分别含3～7条区带，分子量最低14．6KD，最高87.6KD．说明目前国产蛇毒酶制品纯度和质量较差。
Enzymatic activity and safety of snake venom antithrombotics extracted from Agkistrodon, Agkistrodon acutus and Agkistrodon acutus venom were analyzed. The samples tested arginine esterase activity can meet the requirements, and some also exceed the factory specifications of 1 to 3 times, but the qualitative test of thrombin activity only 68.1% (64/94 batches) were positive. Hemorrhagic toxicity and neurotoxicity testing, 14.4% and 38.5% of the samples can not pass. By SDS-PAGE analysis of purity, the samples were tested containing 3-7 bands, the lowest molecular weight 14.6KD, the highest 87.6KD. Description of the current domestic products snake venom purity and quality of the poor.